3di2: Difference between revisions

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{{Seed}}
[[Image:3di2.png|left|200px]]
[[Image:3di2.jpg|left|200px]]


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{{STRUCTURE_3di2|  PDB=3di2  |  SCENE=  }}  
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===Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain===
===Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain===


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{{ABSTRACT_PUBMED_19141282}}


==Disease==
==About this Structure==
Known disease associated with this structure: Severe combined immunodeficiency, T-cell negative, B-cell/natural killer cell-positive type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=146661 146661]], Multiple sclerosis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=146661 146661]]
[[3di2]] is a 4 chain structure of [[Interleukin]] and [[Interleukin receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DI2 OCA].


==About this Structure==
==See Also==
3DI2 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DI2 OCA].
*[[Interleukin|Interleukin]]
*[[Interleukin receptor|Interleukin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:19141282</ref><references group="xtra"/>
<ref group="xtra">PMID:019141282</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dohm, J A.]]
[[Category: Dohm, J A.]]
[[Category: McElroy, C A.]]
[[Category: McElroy, C A.]]
[[Category: Walsh, S T.R.]]
[[Category: Walsh, S T.R.]]
[[Category: Alternative splicing]]
[[Category: Cytokine]]
[[Category: Cytokine]]
[[Category: Cytokine receptor]]
[[Category: Cytokine receptor]]
[[Category: Cytokine/cytokine receptor complex]]
[[Category: Cytokine-cytokine receptor complex]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Ectodomain]]
[[Category: Ectodomain]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Scid]]
[[Category: Scid]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:45:38 2009''

Revision as of 15:30, 26 July 2012

File:3di2.png

Template:STRUCTURE 3di2

Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain

Template:ABSTRACT PUBMED 19141282

About this Structure

3di2 is a 4 chain structure of Interleukin and Interleukin receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. McElroy CA, Dohm JA, Walsh ST. Structural and biophysical studies of the human IL-7/IL-7Ralpha complex. Structure. 2009 Jan 14;17(1):54-65. PMID:19141282 doi:10.1016/j.str.2008.10.019

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