2rn5: Difference between revisions

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{{Seed}}
[[Image:2rn5.png|left|200px]]
[[Image:2rn5.png|left|200px]]


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{{STRUCTURE_2rn5|  PDB=2rn5  |  SCENE=  }}  
{{STRUCTURE_2rn5|  PDB=2rn5  |  SCENE=  }}  


===Humal Insulin Mutant B31Lys-B32Arg===
===Humal Insulin Mutant B31Lys-B32Arg===


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{{ABSTRACT_PUBMED_18491415}}
{{ABSTRACT_PUBMED_18491415}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], Hyperproinsulinemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], MODY, one form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]]
[[2rn5]] is a 2 chain structure of [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RN5 OCA].


==About this Structure==
==See Also==
2RN5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RN5 OCA].
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:18491415</ref><references group="xtra"/>
<ref group="xtra">PMID:018491415</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bocian, W.]]
[[Category: Bocian, W.]]
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[[Category: Human insulin mutant]]
[[Category: Human insulin mutant]]
[[Category: Monomer]]
[[Category: Monomer]]
[[Category: Nmr]]
[[Category: Pharmaceutical]]
[[Category: Secreted]]
[[Category: Secreted]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:17:43 2009''

Revision as of 01:57, 26 July 2012

File:2rn5.png

Template:STRUCTURE 2rn5

Humal Insulin Mutant B31Lys-B32Arg

Template:ABSTRACT PUBMED 18491415

About this Structure

2rn5 is a 2 chain structure of Molecular Playground/Insulin with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  1. Bocian W, Borowicz P, Mikolajczyk J, Sitkowski J, Tarnowska A, Bednarek E, Glabski T, Tejchman-Malecka B, Bogiel M, Kozerski L. NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer. Biopolymers. 2008 Oct;89(10):820-30. PMID:18491415 doi:10.1002/bip.21018

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