2gza: Difference between revisions

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[[Image:2gza.gif|left|200px]]<br /><applet load="2gza" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:2gza.gif|left|200px]]<br /><applet load="2gza" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2gza, resolution 2.600Å" />

'''Crystal structure of the VirB11 ATPase from the Brucella Suis type IV secretion system in complex with sulphate'''<br />

==Overview==

VirB11 ATPases are hexameric assemblies that power type IV secretion, systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like, that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring, structure formed by the N-terminal and C-terminal domains of each monomer., However, the monomer differs dramatically from that of Hp0525 by a large, domain swap that leaves the hexameric assembly intact but profoundly, alters the nucleotide-binding site and the interface between subunits.

VirB11 ATPases are hexameric assemblies that power type IV secretion systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring structure formed by the N-terminal and C-terminal domains of each monomer. However, the monomer differs dramatically from that of Hp0525 by a large domain swap that leaves the hexameric assembly intact but profoundly alters the nucleotide-binding site and the interface between subunits.

==About this Structure==

2GZA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Brucella_suis Brucella suis] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=2GZA OCA].

2GZA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Brucella_suis Brucella suis] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZA OCA].

==Reference==

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[[Category: secretion]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Wed Nov~~ 21 11:28:~~07 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:36:37 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2gza.gif|left|200px]]<br /><applet load="2gza" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:2gza.gif|left|200px]]<br /><applet load="2gza" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2gza, resolution 2.600&Aring;" />
 '''Crystal structure of the VirB11 ATPase from the Brucella Suis type IV secretion system in complex with sulphate'''<br />
 ==Overview==
-VirB11 ATPases are hexameric assemblies that power type IV secretion, systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like, that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring, structure formed by the N-terminal and C-terminal domains of each monomer., However, the monomer differs dramatically from that of Hp0525 by a large, domain swap that leaves the hexameric assembly intact but profoundly, alters the nucleotide-binding site and the interface between subunits.
+VirB11 ATPases are hexameric assemblies that power type IV secretion systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring structure formed by the N-terminal and C-terminal domains of each monomer. However, the monomer differs dramatically from that of Hp0525 by a large domain swap that leaves the hexameric assembly intact but profoundly alters the nucleotide-binding site and the interface between subunits.
 ==About this Structure==
-GZA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Brucella_suis Brucella suis] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2GZA OCA].
+GZA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Brucella_suis Brucella suis] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZA OCA].
 ==Reference==
@@ Line 22: / Line 22: @@
 [[Category: secretion]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 11:28:07 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:36:37 2008''