2h67: Difference between revisions

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{{Seed}}
[[Image:2h67.png|left|200px]]
[[Image:2h67.png|left|200px]]


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{{STRUCTURE_2h67|  PDB=2h67  |  SCENE=  }}  
{{STRUCTURE_2h67|  PDB=2h67  |  SCENE=  }}  


===NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures===
===NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures===


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{{ABSTRACT_PUBMED_16728398}}
{{ABSTRACT_PUBMED_16728398}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], Hyperproinsulinemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], MODY, one form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]]
[[2h67]] is a 2 chain structure of [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H67 OCA].


==About this Structure==
==See Also==
2H67 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H67 OCA].
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16728398</ref><references group="xtra"/>
<ref group="xtra">PMID:016728398</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arvan, P.]]
[[Category: Arvan, P.]]
Line 35: Line 23:
[[Category: Weiss, M A.]]
[[Category: Weiss, M A.]]
[[Category: Hormone]]
[[Category: Hormone]]
[[Category: Hormone-growth factor complex]]
[[Category: Human insulin]]
[[Category: Human insulin]]
[[Category: Mutant]]
[[Category: Mutant]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:52:38 2009''

Revision as of 13:25, 27 July 2012

File:2h67.png

Template:STRUCTURE 2h67

NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16728398

About this Structure

2h67 is a 2 chain structure of Molecular Playground/Insulin with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  1. Hua QX, Liu M, Hu SQ, Jia W, Arvan P, Weiss MA. A conserved histidine in insulin is required for the foldability of human proinsulin: structure and function of an ALAB5 analog. J Biol Chem. 2006 Aug 25;281(34):24889-99. Epub 2006 May 25. PMID:16728398 doi:10.1074/jbc.M602617200

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