2wc0: Difference between revisions

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{{Seed}}
[[Image:2wc0.png|left|200px]]
[[Image:2wc0.png|left|200px]]


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{{STRUCTURE_2wc0|  PDB=2wc0  |  SCENE=  }}  
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===CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN===
===CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN===


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{{ABSTRACT_PUBMED_19321446}}


==About this Structure==
==About this Structure==
2WC0 is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC0 OCA].  
[[2wc0]] is a 6 chain structure of [[Insulin-Degrading Enzyme]] and [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC0 OCA].  
 
==See Also==
*[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]]
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19321446</ref><references group="xtra"/>
<ref group="xtra">PMID:019321446</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Insulysin]]
[[Category: Insulysin]]
Line 33: Line 25:
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cytoplasm]]
[[Category: Dioxane]]
[[Category: Dioxane]]
[[Category: Disulfide bond]]
[[Category: Disulfide bond]]
Line 40: Line 31:
[[Category: Human insulin-degrading enzyme]]
[[Category: Human insulin-degrading enzyme]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hormone complex]]
[[Category: Hydrolase/hormone]]
[[Category: Hydrolase/hormone]]
[[Category: Insulin]]
[[Category: Insulin]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Metalloprotease]]
[[Category: Metalloprotease]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr  8 20:04:37 2009''

Revision as of 20:21, 26 July 2012

File:2wc0.png

Template:STRUCTURE 2wc0

CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN

Template:ABSTRACT PUBMED 19321446

About this Structure

2wc0 is a 6 chain structure of Insulin-Degrading Enzyme and Molecular Playground/Insulin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Manolopoulou M, Guo Q, Malito E, Schilling AB, Tang WJ. Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme. J Biol Chem. 2009 May 22;284(21):14177-88. Epub 2009 Mar 25. PMID:19321446 doi:10.1074/jbc.M900068200

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