2g8n: Difference between revisions

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Revision as of 09:38, 26 December 2010

File:2g8n.png

Template:STRUCTURE 2g8n

Structure of hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy

Template:ABSTRACT PUBMED 16942016

About this Structure

2g8n is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Grunewald GL, Seim MR, Regier RC, Martin JL, Gee CL, Drinkwater N, Criscione KR. Comparison of the binding of 3-fluoromethyl-7-sulfonyl-1,2,3,4-tetrahydroisoquinolines with their isosteric sulfonamides to the active site of phenylethanolamine N-methyltransferase. J Med Chem. 2006 Sep 7;49(18):5424-33. PMID:16942016 doi:https://dx.doi.org/10.1021/jm060466d

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