2obf: Difference between revisions

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Revision as of 23:48, 26 December 2010

File:2obf.png

Template:STRUCTURE 2obf

Structure of K57A hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy (SAH)

Template:ABSTRACT PUBMED 17845018

About this Structure

2obf is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385

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