Aldose Reductase: Difference between revisions
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[[Image:2bgq.png|left|200px|thumb|Crystal structure of Aldose Reductase [[2bgq]]]] | [[Image:2bgq.png|left|200px|thumb|Crystal structure of Aldose Reductase [[2bgq]]]] | ||
{{STRUCTURE_2bgq| PDB=2bgq | SIZE=300| SCENE= |right|CAPTION=Aldose Reductase [[2bgq]] }} | {{STRUCTURE_2bgq| PDB=2bgq | SIZE=300| SCENE=Aldose_Reductase/Cv/1 |right|CAPTION=Aldose Reductase [[2bgq]] }} | ||
[[Aldose Reductase]] (AldR) is an NADPH-dependent enzyme which reduces aldehydes and carbonyls. It reduces glucose to sorbitol in the glucose metabolism pathway. The AldR is implicated in diabetics and causing Iodine Deficiency Disorder (IDD) and its treatment involves the use of IDD inhibitors of AldR. The images at the left and at the right correspond to one representative AldR, ''i.e.'' the crystal structure of barley apo-Aldose Reductase ([[2bgq]]). | [[Aldose Reductase]] (AldR) is an NADPH-dependent enzyme which reduces aldehydes and carbonyls. It reduces glucose to sorbitol in the glucose metabolism pathway. The AldR is implicated in diabetics and causing Iodine Deficiency Disorder (IDD) and its treatment involves the use of IDD inhibitors of AldR. The images at the left and at the right correspond to one representative AldR, ''i.e.'' the crystal structure of barley apo-Aldose Reductase ([[2bgq]]). | ||
