Im8

Im8 is the immunity protein produced by E. coli alongside Colicin E8 to protect itself against Colicin E8's DNase Activity, by binding to the enzymatic C domain and inhibiting its activity. This occurs to prevent the cell that produces the colicin from being killed. Im8 is later released when the Colicin binds to BtuB, the outer membrane receptor on the target cell.

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D load='1gxg' size='350' frame='false' scene=
1gxg, 1 NMR models (default scene)
Related:	1imy, 1imz
Structural annotation: Resources: CATH : 1Gxga00 InterPro : Ipr000290 Pfam : PF01320 SCOP : d1gxga_ UniProt : P09881
Functional annotation: Biological process: bacteriocin immunity Molecular function: toxin binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

3D structures of colicin-E8 immunitiy protein

Colicin Immunity Protein

Proteopedia Page Contributors and Editors (what is this?)

Gemma McGoldrick, Michal Harel