1w72: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[1w72]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W72 OCA]. | [[1w72]] is a 10 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W72 OCA]. | ||
==See Also== | |||
*[[Beta-2 microglobulin]] | |||
*[[Major histocompatibility complex]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:015537658</ref><ref group="xtra">PMID:010884427</ref><ref group="xtra">PMID:012097420</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Alings, C.]] | [[Category: Alings, C.]] | ||
| Line 36: | Line 40: | ||
[[Category: Wille, G.]] | [[Category: Wille, G.]] | ||
[[Category: Ziegler, A.]] | [[Category: Ziegler, A.]] | ||
[[Category: Hla/fab fragment]] | [[Category: Hla/fab fragment]] | ||
[[Category: Human leucocyte antigen]] | [[Category: Human leucocyte antigen]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Mhc-i]] | [[Category: Mhc-i]] | ||
[[Category: Peptide-specific fab]] | [[Category: Peptide-specific fab]] | ||
[[Category: Tcr-like binding]] | [[Category: Tcr-like binding]] | ||
Revision as of 06:01, 24 August 2011
CRYSTAL STRUCTURE OF HLA-A1:MAGE-A1 IN COMPLEX WITH FAB-HYB3
Template:ABSTRACT PUBMED 15537658
About this Structure
1w72 is a 10 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hulsmeyer M, Chames P, Hillig RC, Stanfield RL, Held G, Coulie PG, Alings C, Wille G, Saenger W, Uchanska-Ziegler B, Hoogenboom HR, Ziegler A. A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3. J Biol Chem. 2005 Jan 28;280(4):2972-80. Epub 2004 Nov 10. PMID:15537658 doi:10.1074/jbc.M411323200
- Chames P, Hufton SE, Coulie PG, Uchanska-Ziegler B, Hoogenboom HR. Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7969-74. PMID:10884427
- Chames P, Willemsen RA, Rojas G, Dieckmann D, Rem L, Schuler G, Bolhuis RL, Hoogenboom HR. TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity. J Immunol. 2002 Jul 15;169(2):1110-8. PMID:12097420 doi:10.4049/jimmunol.169.2.1110