2hh4: Difference between revisions

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{{Seed}}
[[Image:2hh4.png|left|200px]]
[[Image:2hh4.png|left|200px]]


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{{STRUCTURE_2hh4|  PDB=2hh4  |  SCENE=  }}  
{{STRUCTURE_2hh4|  PDB=2hh4  |  SCENE=  }}  


===NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures===
===NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures===


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The line below this paragraph, {{ABSTRACT_PUBMED_16762918}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_16762918}}
{{ABSTRACT_PUBMED_16762918}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], Hyperproinsulinemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], MODY, one form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]]
[[2hh4]] is a 2 chain structure of [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HH4 OCA].


==About this Structure==
==See Also==
2HH4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HH4 OCA].
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16762918</ref><references group="xtra"/>
<ref group="xtra">PMID:016762918</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hu, S Q.]]
[[Category: Hu, S Q.]]
Line 34: Line 22:
[[Category: Weiss, M A.]]
[[Category: Weiss, M A.]]
[[Category: Hormone]]
[[Category: Hormone]]
[[Category: Hormone-growth factor complex]]
[[Category: Human insulin]]
[[Category: Human insulin]]
[[Category: Mutant]]
[[Category: Mutant]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:09:06 2009''

Revision as of 15:41, 25 July 2012

File:2hh4.png

Template:STRUCTURE 2hh4

NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16762918

About this Structure

2hh4 is a 2 chain structure of Molecular Playground/Insulin with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  1. Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain. J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:16762918 doi:https://dx.doi.org/10.1074/jbc.M602691200

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