3h4g: Difference between revisions

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{{Seed}}
[[Image:3h4g.png|left|200px]]
[[Image:3h4g.jpg|left|200px]]


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{{STRUCTURE_3h4g|  PDB=3h4g  |  SCENE=  }}  
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===Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity===
===Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity===


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{{ABSTRACT_PUBMED_16107153}}


==About this Structure==
==About this Structure==
3H4G is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ao0 2ao0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H4G OCA].  
[[3h4g]] is a 1 chain structure of [[Alcohol dehydrogenase]] and [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ao0 2ao0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H4G OCA].  
 
==See Also==
*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]
*[[Aldose Reductase|Aldose Reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16107153</ref><references group="xtra"/>
<ref group="xtra">PMID:016107153</ref><references group="xtra"/>
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Carbone, V.]]
[[Category: Carbone, V.]]
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[[Category: Ternary complex]]
[[Category: Ternary complex]]
[[Category: Tim barrel]]
[[Category: Tim barrel]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May  6 09:53:42 2009''

Revision as of 05:22, 26 July 2012

File:3h4g.png

Template:STRUCTURE 3h4g

Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity

Template:ABSTRACT PUBMED 16107153

About this Structure

3h4g is a 1 chain structure of Alcohol dehydrogenase and Aldose Reductase with sequence from Sus scrofa. This structure supersedes the now removed PDB entry 2ao0. Full crystallographic information is available from OCA.

See Also

Reference

  1. El-Kabbani O, Carbone V, Darmanin C, Oka M, Mitschler A, Podjarny A, Schulze-Briese C, Chung RP. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. J Med Chem. 2005 Aug 25;48(17):5536-42. PMID:16107153 doi:10.1021/jm050412o

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