2guo: Difference between revisions

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{{Seed}}
[[Image:2guo.png|left|200px]]
[[Image:2guo.png|left|200px]]


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{{STRUCTURE_2guo|  PDB=2guo  |  SCENE=  }}  
{{STRUCTURE_2guo|  PDB=2guo  |  SCENE=  }}  


===Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide===
===Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide===


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{{ABSTRACT_PUBMED_17719062}}
{{ABSTRACT_PUBMED_17719062}}


==Disease==
==About this Structure==
Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Ankylosing spondylitis, susceptibility to, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Stevens-Johnson syndrome, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]]
[[2guo]] is a 6 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUO OCA].


==About this Structure==
==See Also==
2GUO is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUO OCA].
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Major histocompatibility complex|Major histocompatibility complex]]


==Reference==
==Reference==
<ref group="xtra">PMID:17719062</ref><references group="xtra"/>
<ref group="xtra">PMID:017719062</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Baker, B M.]]
[[Category: Baker, B M.]]
Line 32: Line 21:
[[Category: Cancer vaccine]]
[[Category: Cancer vaccine]]
[[Category: Hla-a2]]
[[Category: Hla-a2]]
[[Category: Immune system]]
[[Category: Melan-a/mart-1 peptide]]
[[Category: Melan-a/mart-1 peptide]]
[[Category: Melanoma]]
[[Category: Melanoma]]
[[Category: Mhc class i]]
[[Category: Mhc class i]]
[[Category: Nonapeptide]]
[[Category: Nonapeptide]]
[[Category: X-ray crystallography]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:00:05 2009''

Revision as of 06:13, 26 July 2012

File:2guo.png

Template:STRUCTURE 2guo

Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide

Template:ABSTRACT PUBMED 17719062

About this Structure

2guo is a 6 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:17719062 doi:10.1016/j.jmb.2007.07.025

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