2h5s: Difference between revisions

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{{Seed}}
[[Image:2h5s.png|left|200px]]
[[Image:2h5s.png|left|200px]]


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{{STRUCTURE_2h5s|  PDB=2h5s  |  SCENE=  }}  
{{STRUCTURE_2h5s|  PDB=2h5s  |  SCENE=  }}  


===SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase===
===SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase===


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{{ABSTRACT_PUBMED_17017804}}
{{ABSTRACT_PUBMED_17017804}}


==About this Structure==
==About this Structure==
2H5S is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5S OCA].  
[[2h5s]] is a 1 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5S OCA].  
 
==See Also==
*[[Beta-lactamase|Beta-lactamase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17017804</ref><references group="xtra"/>
<ref group="xtra">PMID:017017804</ref><references group="xtra"/>
[[Category: Hydrolase]]
[[Category: Beta-lactamase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: Akker, F van den.]]
[[Category: Akker, F van den.]]
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[[Category: Beta-lactamase inhibitor]]
[[Category: Beta-lactamase inhibitor]]
[[Category: Drug design]]
[[Category: Drug design]]
 
[[Category: Hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:42:11 2009''

Revision as of 11:48, 26 July 2012

File:2h5s.png

Template:STRUCTURE 2h5s

SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase

Template:ABSTRACT PUBMED 17017804

About this Structure

2h5s is a 1 chain structure of Beta-lactamase with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Padayatti PS, Sheri A, Totir MA, Helfand MS, Carey MP, Anderson VE, Carey PR, Bethel CR, Bonomo RA, Buynak JD, van den Akker F. Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone. J Am Chem Soc. 2006 Oct 11;128(40):13235-42. PMID:17017804 doi:10.1021/ja063715w

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