2k05: Difference between revisions

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{{Seed}}
[[Image:2k05.png|left|200px]]
[[Image:2k05.png|left|200px]]


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{{STRUCTURE_2k05|  PDB=2k05  |  SCENE=  }}  
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===Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21===
===Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21===


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{{ABSTRACT_PUBMED_18799424}}
{{ABSTRACT_PUBMED_18799424}}


==Disease==
==About this Structure==
Known disease associated with this structure: Myelokathexis, isolated OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=162643 162643]], WHIM syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=162643 162643]]
[[2k05]] is a 4 chain structure of [[CXC chemokine receptor type 4]] and [[Stromal Derived Factor 1]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K05 OCA].


==About this Structure==
==See Also==
2K05 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K05 OCA].
*[[CXC chemokine receptor type 4|CXC chemokine receptor type 4]]
*[[Stromal Derived Factor 1|Stromal Derived Factor 1]]


==Reference==
==Reference==
<ref group="xtra">PMID:18799424</ref><references group="xtra"/>
<ref group="xtra">PMID:018799424</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peterson, F C.]]
[[Category: Peterson, F C.]]
[[Category: Veldkamp, C T.]]
[[Category: Veldkamp, C T.]]
[[Category: Volkman, B F.]]
[[Category: Volkman, B F.]]
[[Category: Alternative splicing]]
[[Category: Chemokine]]
[[Category: Chemokine]]
[[Category: Chemotaxis]]
[[Category: Chemotaxis]]
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[[Category: Transducer]]
[[Category: Transducer]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:34:33 2009''

Revision as of 00:30, 27 July 2012

File:2k05.png

Template:STRUCTURE 2k05

Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21

Template:ABSTRACT PUBMED 18799424

About this Structure

2k05 is a 4 chain structure of CXC chemokine receptor type 4 and Stromal Derived Factor 1 with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  1. Veldkamp CT, Seibert C, Peterson FC, De la Cruz NB, Haugner JC 3rd, Basnet H, Sakmar TP, Volkman BF. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci Signal. 2008 Sep 16;1(37):ra4. PMID:18799424 doi:1/37/ra4

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