3kxg: Difference between revisions
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[[Image:3kxg.png|left|200px]] | [[Image:3kxg.png|left|200px]] | ||
{{STRUCTURE_3kxg| PDB=3kxg | SCENE= }} | {{STRUCTURE_3kxg| PDB=3kxg | SCENE= }} | ||
===Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)=== | ===Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)=== | ||
{{ABSTRACT_PUBMED_21513497}} | {{ABSTRACT_PUBMED_21513497}} | ||
==About this Structure== | ==About this Structure== | ||
[[3kxg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXG OCA]. | [[3kxg]] is a 1 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXG OCA]. | ||
==See Also== | |||
*[[Casein kinase|Casein kinase]] | |||
==Reference== | ==Reference== | ||
Revision as of 02:01, 27 July 2012
Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)
Template:ABSTRACT PUBMED 21513497
About this Structure
3kxg is a 1 chain structure of Casein kinase with sequence from Zea mays. Full crystallographic information is available from OCA.
See Also
Reference
- Sarno S, Papinutto E, Franchin C, Bain J, Elliott M, Meggio F, Kazimierczuk Z, Orzeszko A, Zanotti G, Battistutta R, Pinna LA. Atp Site-Directed Inhibitors of Protein Kinase Ck2: An Update. Curr Top Med Chem. 2011 Mar 29. PMID:21513497
- Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA. Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem Biol. 2005 Nov;12(11):1211-9. PMID:16298300 doi:10.1016/j.chembiol.2005.08.015
- Battistutta R, Mazzorana M, Cendron L, Bortolato A, Sarno S, Kazimierczuk Z, Zanotti G, Moro S, Pinna LA. The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules. Chembiochem. 2007 Oct 15;8(15):1804-9. PMID:17768728 doi:10.1002/cbic.200700307