2erj: Difference between revisions

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{{Seed}}
[[Image:2erj.png|left|200px]]
[[Image:2erj.png|left|200px]]


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{{STRUCTURE_2erj|  PDB=2erj  |  SCENE=  }}  
{{STRUCTURE_2erj|  PDB=2erj  |  SCENE=  }}  


===Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2===
===Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2===


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{{ABSTRACT_PUBMED_16477002}}
{{ABSTRACT_PUBMED_16477002}}


==Disease==
==About this Structure==
Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]]
[[2erj]] is a 8 chain structure of [[Interleukin]] and [[Interleukin receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA].


==About this Structure==
==See Also==
2ERJ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA].
*[[Interleukin|Interleukin]]
*[[Interleukin receptor|Interleukin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:16477002</ref><references group="xtra"/>
<ref group="xtra">PMID:016477002</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Debler, E W.]]
[[Category: Debler, E W.]]
[[Category: Stauber, D J.]]
[[Category: Stauber, D J.]]
[[Category: Wilson, I A.]]
[[Category: Wilson, I A.]]
[[Category: Immune system-cytokine complex]]
[[Category: Interleukin-2]]
[[Category: Interleukin-2]]
[[Category: Interleukin-2 alpha receptor]]
[[Category: Interleukin-2 alpha receptor]]
[[Category: Interleukin-2 beta receptor]]
[[Category: Interleukin-2 beta receptor]]
[[Category: Interleukin-2 gamma receptor]]
[[Category: Interleukin-2 gamma receptor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:00:57 2009''

Revision as of 12:25, 27 July 2012

File:2erj.png

Template:STRUCTURE 2erj

Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2

Template:ABSTRACT PUBMED 16477002

About this Structure

2erj is a 8 chain structure of Interleukin and Interleukin receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:16477002

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