2pf8: Difference between revisions

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===Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is equal to concentration of IDD594.===
===Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is equal to concentration of IDD594.===


{{ABSTRACT_PUBMED_22752989}}


==About this Structure==
==About this Structure==
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==See Also==
==See Also==
*[[Aldose Reductase|Aldose Reductase]]
*[[Aldose Reductase|Aldose Reductase]]
==Reference==
<ref group="xtra">PMID:022752989</ref><references group="xtra"/>
[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 05:07, 22 August 2012

File:2pf8.png

Template:STRUCTURE 2pf8

Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is equal to concentration of IDD594.

Template:ABSTRACT PUBMED 22752989

About this Structure

2pf8 is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cousido-Siah A, Petrova T, Hazemann I, Mitschler A, Ruiz FX, Howard E, Ginell S, Atmanene C, Van Dorsselaer A, Sanglier-Cianferani S, Joachimiak A, Podjarny A. Crystal packing modifies ligand binding affinity: The case of aldose reductase. Proteins. 2012 Jul 2. doi: 10.1002/prot.24136. PMID:22752989 doi:10.1002/prot.24136

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