3c6m: Difference between revisions

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{{Seed}}
[[Image:3c6m.png|left|200px]]
[[Image:3c6m.png|left|200px]]


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{{STRUCTURE_3c6m|  PDB=3c6m  |  SCENE=  }}  
{{STRUCTURE_3c6m|  PDB=3c6m  |  SCENE=  }}  


===Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine===
===Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine===


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{{ABSTRACT_PUBMED_18367445}}
{{ABSTRACT_PUBMED_18367445}}


==Disease==
==About this Structure==
Known disease associated with this structure: Mental retardation, X-linked, Snyder-Robinson type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300105 300105]], Smith-Magenis syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607642 607642]]
[[3c6m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6M OCA].


==About this Structure==
==See Also==
3C6M is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6M OCA].
*[[Spermidine Synthase|Spermidine Synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18367445</ref><references group="xtra"/>
<ref group="xtra">PMID:018367445</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Spermine synthase]]
[[Category: Spermine synthase]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:34:21 2009''

Revision as of 12:41, 20 October 2012

File:3c6m.png

Template:STRUCTURE 3c6m

Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine

Template:ABSTRACT PUBMED 18367445

About this Structure

3c6m is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wu H, Min J, Zeng H, McCloskey DE, Ikeguchi Y, Loppnau P, Michael AJ, Pegg AE, Plotnikov AN. Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism. J Biol Chem. 2008 Jun 6;283(23):16135-46. Epub 2008 Mar 26. PMID:18367445 doi:https://dx.doi.org/10.1074/jbc.M710323200

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