3fal: Difference between revisions

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Revision as of 21:26, 20 October 2012

File:3fal.png

Template:STRUCTURE 3fal

humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186

Template:ABSTRACT PUBMED 18800767

About this Structure

3fal is a 4 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J Med Chem. 2008 Sep 25;51(18):5758-65. PMID:18800767 doi:10.1021/jm800612u

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