Semaphorin: Difference between revisions
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{{STRUCTURE_3nvn| PDB=3nvn | SIZE=400| SCENE= |right|CAPTION=Glycosylated human semaphorin 7A (grey) complex with plexin-C1 (green) and Ca+2 ion, [[3nvn]] }} | {{STRUCTURE_3nvn| PDB=3nvn | SIZE=400| SCENE= |right|CAPTION=Glycosylated human semaphorin 7A (grey) complex with plexin-C1 (green) and Ca+2 ion (green), [[3nvn]] }} | ||
'''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | '''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | ||
Revision as of 09:42, 15 November 2012
Template:STRUCTURE 3nvn
Semaphorin (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics.
3D structures of semaphorin
SEMA 3
1q47 – mSEMA 3A – mouse
SEMA 4
1olz – hSEMA 4D extracellular domain – human
3ol2 - hSEMA 4D extracellular domain + plexin-B1
SEMA 6
3afc, 3okw - mSEMA 6A extracellular domain
3al8 - mSEMA 6A + plexin-A2
