Disintegrin

File:1z1x.png

Crystal Structure of Disintegrin 1z1x

Disintegrins are a family of toxins from viper venoms which inhibit platelet aggregation and cell adhesion. The images at the left and at the right correspond to one representative Disintegrin, i.e. the crystal structure of Disintegrin from Echis carinatus (1z1x).

3D Structures of Disintegrin

Update January 2013

2w9o, 2w9u, 2w9v, 2w9w – jerdostatin residues 68-110 – Trimeresurus jerdonii – NMR
1j2l – trimestatin - Trimeresurus flavovidrius
2pjf, 1q7i, 1q7j – Cr rhodostoxin residues 1-68 – Calloselasma rhodostoma – NMR
2pjg, 2pji, 2ljv - Cr rhodostoxin (mutant) – NMR
3uci - Cr rhodostoxin (mutant)
1z1x, 1tej – Ec disintegrin – Echis carinatus
1rmr – Ec schistatin
1ro3, 2ech – Ec echistatin - NMR
1l3x – salmosin – Gloydius brevicaudus – NMR
1mpz – obtustatin – Macrovipera obtusa - NMR
1dem – dendrotoxin I – black mamba
1den - dendrotoxin I - NMR
1dtk - dendrotoxin K- NMR
1dtx – α-dendrotoxin - Eastern green mamba
3c05 – acostatin-α residues 48-109+acostatin-β residues 419-482 – copperhead
3dsl – bothropasin - Jararaca

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Eric Martz, Joel L. Sussman