3q90: Difference between revisions

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[[Image:3q90.jpg|left|200px]]
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{{STRUCTURE_3q90|  PDB=3q90  |  SCENE=  }}  
{{STRUCTURE_3q90|  PDB=3q90  |  SCENE=  }}  
===Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1===
===Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1===


==Function==
[[http://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN]] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref> 


==About this Structure==
==About this Structure==
[[3q90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA].  
[[3q90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA].  
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H.]]
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[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Welin, M.]]
[[Category: Welin, M.]]
[[Category: Dna and rna binding]]
[[Category: Hydrolase]]
[[Category: Nucleus]]
[[Category: Plasma membrane]]
[[Category: Protein binding and helicase]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]