2g71: Difference between revisions

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[[Image:2g71.png|left|200px]]
{{STRUCTURE_2g71|  PDB=2g71  |  SCENE=  }}  
{{STRUCTURE_2g71|  PDB=2g71  |  SCENE=  }}  
===Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy===
===Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy===
{{ABSTRACT_PUBMED_17845018}}


{{ABSTRACT_PUBMED_17845018}}
==Function==
[[http://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN]] Converts noradrenaline to adrenaline.


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:017845018</ref><references group="xtra"/>
<ref group="xtra">PMID:017845018</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]

Revision as of 06:19, 2 October 2013

Template:STRUCTURE 2g71

Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy

Template:ABSTRACT PUBMED 17845018

Function

[PNMT_HUMAN] Converts noradrenaline to adrenaline.

About this Structure

2g71 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385

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