4bkk: Difference between revisions
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{{STRUCTURE_4bkk| PDB=4bkk | SCENE= }} | |||
===The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.=== | |||
{{ABSTRACT_PUBMED_23677789}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/NCAP_HRSVA NCAP_HRSVA]] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.<ref>PMID:9299631</ref> | |||
==About this Structure== | |||
[[4bkk]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus_a_strain_long Human respiratory syncytial virus a strain long]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKK OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023677789</ref><references group="xtra"/><references/> | |||
[[Category: Human respiratory syncytial virus a strain long]] | |||
[[Category: Bakker, S E.]] | |||
[[Category: Bhella, D.]] | |||
[[Category: Conner, E.]] | |||
[[Category: Duquerroy, S.]] | |||
[[Category: Eleouet, J F.]] | |||
[[Category: Galloux, M.]] | |||
[[Category: Loney, C.]] | |||
[[Category: Rey, F A.]] | |||
[[Category: Viral protein-rna complex]] | |||
Revision as of 09:40, 30 October 2013
The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.
Template:ABSTRACT PUBMED 23677789
Function
[NCAP_HRSVA] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.[1]
About this Structure
4bkk is a 24 chain structure with sequence from Human respiratory syncytial virus a strain long. Full crystallographic information is available from OCA.
Reference
- Bakker SE, Duquerroy S, Galloux M, Loney C, Conner E, Eleouet JF, Rey FA, Bhella D. The respiratory syncytial virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid. J Gen Virol. 2013 Aug;94(Pt 8):1734-8. doi: 10.1099/vir.0.053025-0. Epub 2013 May, 15. PMID:23677789 doi:https://dx.doi.org/10.1099/vir.0.053025-0
- ↑ Fearns R, Peeples ME, Collins PL. Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome. Virology. 1997 Sep 15;236(1):188-201. PMID:9299631 doi:10.1006/viro.1997.8734
