Sphingomyelinase: Difference between revisions
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{{STRUCTURE_1zwx| PDB=1zwx | SIZE=400| SCENE= |right|CAPTION=Sphingomyelinase complex with | {{STRUCTURE_1zwx| PDB=1zwx | SIZE=400| SCENE= |right|CAPTION=Sphingomyelinase complex with glycerol and phosphate ion [[1zwx]] }} | ||
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Revision as of 10:04, 2 January 2014
Sphingomyelinase (SMase) is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide. The SMase is classified into 5 types according to their pH dependence and cation dependence.
3D structures of sphingomyelinase
3rlh, 3rlg – SMase D (mutant) – Loxosceles intermedia
1xx1, 2f9r – SMase I – Loxosceles laeta
1zwx – SMase C – Listeria ivanovii
2ddr, 2dds, 2ddt – BcSMase + cation – Bacillus cereus
2uyr – BcSMase (mutant)
