4k7r: Difference between revisions
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===Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation=== | ===Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation=== | ||
{{ABSTRACT_PUBMED_24099674}} | {{ABSTRACT_PUBMED_24099674}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[4k7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4k7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7R OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024099674</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024099674</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Ecoli]] | ||
[[Category: Bolla, J R.]] | [[Category: Bolla, J R.]] | ||
[[Category: Lei, H T.]] | [[Category: Lei, H T.]] | ||
