3ajv: Difference between revisions
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{{STRUCTURE_3ajv| PDB=3ajv | SCENE= }} | {{STRUCTURE_3ajv| PDB=3ajv | SCENE= }} | ||
===Splicing endonuclease from Aeropyrum pernix=== | ===Splicing endonuclease from Aeropyrum pernix=== | ||
{{ABSTRACT_PUBMED_21050862}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ENDA_AERPE ENDA_AERPE]] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[3ajv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3ajv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpe Aerpe] and [http://en.wikipedia.org/wiki/Aerpx Aerpx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AJV OCA]. | ||
==See Also== | ==See Also== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021050862</ref><references group="xtra"/> | <ref group="xtra">PMID:021050862</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Aerpe]] | ||
[[Category: Aerpx]] | |||
[[Category: TRNA-intron endonuclease]] | [[Category: TRNA-intron endonuclease]] | ||
[[Category: Inaoka, K D.]] | [[Category: Inaoka, K D.]] | ||
Revision as of 14:24, 19 February 2014
Splicing endonuclease from Aeropyrum pernix
Template:ABSTRACT PUBMED 21050862
Function
[ENDA_AERPE] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
About this Structure
3ajv is a 4 chain structure with sequence from Aerpe and Aerpx. Full crystallographic information is available from OCA.
See Also
Reference
- Okuda M, Shiba T, Inaoka DK, Kita K, Kurisu G, Mineki S, Harada S, Watanabe YI, Yoshinari S. A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity. J Mol Biol. 2010 Nov 2. PMID:21050862 doi:10.1016/j.jmb.2010.10.050
