4m61: Difference between revisions

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~~{{STRUCTURE_4m61| PDB=4m61 | SCENE= }}~~

==Crystal structure of unliganded anti-DNA Fab A52==

===Crystal structure of unliganded anti-DNA Fab A52===

~~{{ABSTRACT_PUBMED_24449198}}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4m61]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M61 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M61 FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m61 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m61 RCSB], [http://www.ebi.ac.uk/pdbsum/4m61 PDBsum]</span></td></tr>

<table>

== Publication Abstract from PubMed ==

A52 is a murine monoclonal antibody isolated from autoimmune New Zealand Black/New Zealand White F1 mice that recognizes single and double stranded DNA. This mouse strain spontaneously develops systemic lupus erythematosus-like symptoms and has served as a model for that disease for many years. The 1.62 A crystal structure of the A52 Fab fragment reveals an H3 complementarity determining region with four closely spaced arginine residues, creating a positively charged surface to accommodate bound DNA. Proteins 2014. (c) 2014 Wiley Periodicals, Inc.

~~==About this Structure==~~

Crystal structure determination of anti-DNA Fab A52.,Stanfield RL, Eilat D Proteins. 2014 Jan 22. doi: 10.1002/prot.24514. PMID:24449198<ref>PMID:24449198</ref>

~~[[4m61]] is a 4 chain~~ structure ~~with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4M61 OCA].~~

==~~Reference~~==

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

~~<ref group="xtra">PMID:024449198</ref>~~<references ~~group="xtra"~~/><~~references~~/>

</div>

== References ==

__TOC__

</StructureSection>

[[Category: Mus musculus]]

[[Category: Eilat, D.]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4m61|  PDB=4m61  |  SCENE=  }}
+==Crystal structure of unliganded anti-DNA Fab A52==
-===Crystal structure of unliganded anti-DNA Fab A52===
+<StructureSection load='4m61' size='340' side='right' caption='[[4m61]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
-{{ABSTRACT_PUBMED_24449198}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4m61]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M61 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M61 FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m61 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m61 RCSB], [http://www.ebi.ac.uk/pdbsum/4m61 PDBsum]</span></td></tr>
+<table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+A52 is a murine monoclonal antibody isolated from autoimmune New Zealand Black/New Zealand White F1 mice that recognizes single and double stranded DNA. This mouse strain spontaneously develops systemic lupus erythematosus-like symptoms and has served as a model for that disease for many years. The 1.62 A crystal structure of the A52 Fab fragment reveals an H3 complementarity determining region with four closely spaced arginine residues, creating a positively charged surface to accommodate bound DNA. Proteins 2014. (c) 2014 Wiley Periodicals, Inc.
-==About this Structure==
+Crystal structure determination of anti-DNA Fab A52.,Stanfield RL, Eilat D Proteins. 2014 Jan 22. doi: 10.1002/prot.24514. PMID:24449198<ref>PMID:24449198</ref>
-[[4m61]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M61 OCA].
-==Reference==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<ref group="xtra">PMID:024449198</ref><references group="xtra"/><references/>
+</div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Mus musculus]]
 [[Category: Eilat, D.]]