Trehalulose synthase

<StructureSection load='4gi8' size='340' side='right' caption='Structure of trehalulose synthase complex with sucrose (PDB code 2pwe).' scene=>

Function

Trehalulose synthase (THS) converts sucrose to trehalulose (TH).

Relevance

Since TH is a sugar substitute and is absorbed more slowly than sucrose it can be used in diabetic and sports food and drinks.

3D structures of trehalulose synthase

Updated on 12-August-2014

1zja, 1zjb, 2pwh – PmTHS – Pseudomonas mesoacidophila
4go9, 4go8 – PmTHS (mutant)
4h2c, 4h8h – RhTHS (mutant) - Rhizobium

Trehalulose synthase complex

2pwd, 2pwg – PmTHS + inhibitor
2pwe – PmTHS (mutant) + sucrose
2pwf – PmTHS (mutant) + glucose
4gi6, 4h7v – RhTHS (mutant) + glucose
4gi8 – RhTHS (mutant) + sucrose
4h8v – RhTHS + TH
4gi9 – RhTHS (mutant) + TH
4h8u – RhTHS (mutant) + sucrose + TH
4gia, 4ha1 – RhTHS (mutant) + isomaltulose
4gin – RhTHS (mutant) + inhibitor

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky