2wcn: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2wcn" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
[[ | ==SOLUTION STRUCTURE OF AN LNA-MODIFIED QUADRUPLEX== | ||
<StructureSection load='2wcn' size='340' side='right' caption='[[2wcn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2wcn]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WCN FirstGlance]. <br> | |||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LCG:[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wcn RCSB], [http://www.ebi.ac.uk/pdbsum/2wcn PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Sharp curves: The structure of a locked nucleic acid modified telomeric sequence from Oxytricha nova displays a remarkable folding topology, distinct from the native O. nova quadruplex. Each guanine stretch folds back in a V-shaped turn that puts the first and fourth guanines in the same tetrad, looping over a tetrad with a sharp turn in the DNA backbone, showing how subtle interplay between sequence and conformation defines the folding topology. | |||
Solution structure of a locked nucleic acid modified quadruplex: introducing the V4 folding topology.,Nielsen JT, Arar K, Petersen M Angew Chem Int Ed Engl. 2009;48(17):3099-103. PMID:19308940<ref>PMID:19308940</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
== | |||
< | |||
[[Category: Arar, K.]] | [[Category: Arar, K.]] | ||
[[Category: Nielsen, J T.]] | [[Category: Nielsen, J T.]] | ||
Revision as of 11:25, 20 October 2014
SOLUTION STRUCTURE OF AN LNA-MODIFIED QUADRUPLEX
| ||||||||||||
