3lbj: Difference between revisions
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==Structure of human MDMX protein in complex with a small molecule inhibitor== | |||
<StructureSection load='3lbj' size='340' side='right' caption='[[3lbj]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3lbj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LBJ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WW8:N-[(3S)-1-({6-CHLORO-3-[1-(4-CHLOROBENZYL)-4-PHENYL-1H-IMIDAZOL-5-YL]-1H-INDOL-2-YL}CARBONYL)PYRROLIDIN-3-YL]-N,N,N-TRIMETHYLPROPANE-1,3-DIAMINE'>WW8</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dab|3dab]], [[3lbk|3lbk]], [[3lbl|3lbl]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM4, MDMX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lbj RCSB], [http://www.ebi.ac.uk/pdbsum/3lbj PDBsum]</span></td></tr> | |||
== | </table> | ||
[[3lbj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LBJ OCA]. | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/3lbj_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[MDM4|MDM4]] | *[[MDM4|MDM4]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Czarna, A | [[Category: Czarna, A]] | ||
[[Category: Holak, T A | [[Category: Holak, T A]] | ||
[[Category: Popowicz, G M | [[Category: Popowicz, G M]] | ||
[[Category: Wolf, S | [[Category: Wolf, S]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
Revision as of 08:44, 9 December 2014
Structure of human MDMX protein in complex with a small molecule inhibitor
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