4gq0: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
{{STRUCTURE_4gq0|  PDB=4gq0  |  SCENE=  }}
==Crystal structure of AKR1B10 complexed with NADP+ and Caffeic acid phenethyl ester==
===Crystal structure of AKR1B10 complexed with NADP+ and Caffeic acid phenethyl ester===
<StructureSection load='4gq0' size='340' side='right' caption='[[4gq0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4gq0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3v9q 3v9q]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GQ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GQ0 FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/AK1BA_HUMAN AK1BA_HUMAN]] Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.<ref>PMID:18087047</ref> 
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=QAP:2-PHENYLETHYL+(2E)-3-(3,4-DIHYDROXYPHENYL)PROP-2-ENOATE'>QAP</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gq0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gq0 RCSB], [http://www.ebi.ac.uk/pdbsum/4gq0 PDBsum]</span></td></tr>
[[4gq0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3v9q 3v9q]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GQ0 OCA].  
</table>
 
__TOC__
==Reference==
</StructureSection>
<references group="xtra"/><references/>
[[Category: Human]]
[[Category: Human]]
[[Category: Jing, Z.]]
[[Category: Jing, Z]]
[[Category: Liping, Z.]]
[[Category: Liping, Z]]
[[Category: Shangke, C.]]
[[Category: Shangke, C]]
[[Category: Xiaopeng, H.]]
[[Category: Xiaopeng, H]]
[[Category: Xuehua, Z.]]
[[Category: Xuehua, Z]]
[[Category: Alpha-beta tim barrel]]
[[Category: Alpha-beta tim barrel]]
[[Category: Caffeic acid phenethyl ester and nadp+]]
[[Category: Caffeic acid phenethyl ester and nadp+]]
[[Category: Nadp-dependant oxidoreductase]]
[[Category: Nadp-dependant oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 17:31, 21 December 2014

Crystal structure of AKR1B10 complexed with NADP+ and Caffeic acid phenethyl ester

4gq0, resolution 2.10Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=4gq0&oldid=2149530"