4gq0

Crystal structure of AKR1B10 complexed with NADP+ and Caffeic acid phenethyl ester

spinqualitylabelsall models 4gq0, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gq0 is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3v9q. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: NAP, QAP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AK1BA_HUMAN Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. See Also Aldo-keto reductase 3D structures

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