4kbo: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4kbo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBO FirstGlance]. <br> | <table><tr><td colspan='2'>[[4kbo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBO FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e88|2e88]], [[3atu|3atu]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e88|2e88]], [[3atu|3atu]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRP75, HSPA9, HSPA9B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRP75, HSPA9, HSPA9B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kbo RCSB], [http://www.ebi.ac.uk/pdbsum/4kbo PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kbo RCSB], [http://www.ebi.ac.uk/pdbsum/4kbo PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/GRP75_HUMAN GRP75_HUMAN]] Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone.,Amick J, Schlanger SE, Wachnowsky C, Moseng MA, Emerson CC, Dare M, Luo WI, Ithychanda SS, Nix JC, Cowan JA, Page RC, Misra S Protein Sci. 2014 Mar 29. doi: 10.1002/pro.2466. PMID:24687350<ref>PMID:24687350</ref> | Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone.,Amick J, Schlanger SE, Wachnowsky C, Moseng MA, Emerson CC, Dare M, Luo WI, Ithychanda SS, Nix JC, Cowan JA, Page RC, Misra S Protein Sci. 2014 Mar 29. doi: 10.1002/pro.2466. PMID:24687350<ref>PMID:24687350</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Amick, J | [[Category: Amick, J]] | ||
[[Category: Misra, S | [[Category: Misra, S]] | ||
[[Category: Nix, J C | [[Category: Nix, J C]] | ||
[[Category: Page, R C | [[Category: Page, R C]] | ||
[[Category: Atp binding]] | [[Category: Atp binding]] | ||
[[Category: Atpase]] | [[Category: Atpase]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 15:46, 24 December 2014
Crystal structure of the human Mortalin (GRP75) ATPase domain in the apo form
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