4lsg: Difference between revisions
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==Structure of Mouse P-Glycoprotein== | |||
=== | <StructureSection load='4lsg' size='340' side='right' caption='[[4lsg]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4lsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LSG FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ksb|4ksb]], [[4ksc|4ksc]], [[3g5u|3g5u]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lsg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lsg RCSB], [http://www.ebi.ac.uk/pdbsum/4lsg PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | [[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
<references | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Xenobiotic-transporting ATPase]] | [[Category: Xenobiotic-transporting ATPase]] | ||
[[Category: Chang, G | [[Category: Chang, G]] | ||
[[Category: Szewczyk, P | [[Category: Szewczyk, P]] | ||
[[Category: Abc transporter]] | [[Category: Abc transporter]] | ||
[[Category: Atp binding]] | [[Category: Atp binding]] | ||
Revision as of 09:20, 25 December 2014
Structure of Mouse P-Glycoprotein
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