CD44: Difference between revisions
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<StructureSection load='2jca' size='400' side='right' scene='52/523368/Cv/1' caption='Structure of mouse CD44 hyaluronan-binding domain complex with hyaluronic acid (PDB code [[2jca]])'> | |||
== Function == | == Function == | ||
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CD44 is a potential drug target for treatment of malignant neoplasms. Anti-CD44 antibody treatment lowers hyperglycemia and chronic inflammatory diseases. | CD44 is a potential drug target for treatment of malignant neoplasms. Anti-CD44 antibody treatment lowers hyperglycemia and chronic inflammatory diseases. | ||
</StructureSection> | |||
__TOC__ | |||
==3D structures of CD44== | ==3D structures of CD44== | ||
Revision as of 11:05, 29 November 2015
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3D structures of CD44
Updated on 29-November-2015
2jcq, 4pz4 – hCD44 hyaluronan-binding domain – human
1poz, 2i83 - hCD44 hyaluronan-binding domain – NMR
2jcp - mCD44 hyaluronan-binding domain – mouse
2jcq, 2jcr - mCD44 hyaluronan-binding domain + 8-mer HA
4mrd, 4mre, 4mrf, 4mrg, 4mrh, 4np2, 4np3 - mCD44 hyaluronan-binding domain + inhibitor
4np3 - mCD44 hyaluronan-binding domain + tetrapeptide
