5cnr: Difference between revisions
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==Crystal structure-guided design of self-assembling RNA nano triangles== | |||
<StructureSection load='5cnr' size='340' side='right' caption='[[5cnr]], [[Resolution|resolution]] 2.59Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5cnr]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNR FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p97|4p97]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnr OCA], [http://pdbe.org/5cnr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cnr RCSB], [http://www.ebi.ac.uk/pdbsum/5cnr PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
RNA nanotechnology uses RNA structural motifs to build nanosized architectures that assemble through selective base-pair interactions. Herein, we report the crystal-structure-guided design of highly stable RNA nanotriangles that self-assemble cooperatively from short oligonucleotides. The crystal structure of an 81 nucleotide nanotriangle determined at 2.6 A resolution reveals the so-far smallest circularly closed nanoobject made entirely of double-stranded RNA. The assembly of the nanotriangle architecture involved RNA corner motifs that were derived from ligand-responsive RNA switches, which offer the opportunity to control self-assembly and dissociation. | |||
Crystal-Structure-Guided Design of Self-Assembling RNA Nanotriangles.,Boerneke MA, Dibrov SM, Hermann T Angew Chem Int Ed Engl. 2016 Feb 23. doi: 10.1002/anie.201600233. PMID:26914842<ref>PMID:26914842</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 5cnr" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Boerneke, M]] | [[Category: Boerneke, M]] | ||
[[Category: Dibrov, S]] | |||
[[Category: Hermann, T]] | [[Category: Hermann, T]] | ||
[[Category: | [[Category: Nanotriangle]] | ||
[[Category: Rna]] | |||
[[Category: Self-assembly]] | |||
[[Category: Seneca valley virus]] | |||
Revision as of 03:40, 10 March 2016
Crystal structure-guided design of self-assembling RNA nano triangles
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