User:John S. de Banzie/Sandbox 4: Difference between revisions
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==Yeast U4/U6.U5 tri-snRNP== | ==Yeast U4/U6.U5 tri-snRNP== | ||
<StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'> | <StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'> | ||
The <scene='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6). | The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6). | ||
<scene='72/726441/Rnascene/1'> | Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs. | ||
The U2 snRNP binds to the region highlighted in blue in this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome. | The U2 snRNP <scene name='72/726441/Dockscene/1'>binds to the region </scene>highlighted in blue in this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome. | ||
For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>. | For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>. | ||
Revision as of 15:23, 18 March 2016
Yeast U4/U6.U5 tri-snRNP
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