Matriptase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load=' | <StructureSection load='1eax' size='340' side='right' caption='Structure of human matriptase catalytic domain (grey) complex with Kunitz-type protease inhibitor (green) and glutathione (PDB code [[4isn]]). ' scene=''> | ||
== Function == | == Function == | ||
| Line 12: | Line 12: | ||
== Structural highlights == | == Structural highlights == | ||
ST14 active site has the conformation of a typical serine protease like trypsin or chymotrypsin with the Ser-His-Asp catalytic triad and Gly-Ser oxyanion hole. The inhibitor benzamidine blocks the cataytic triad<ref>PMID:11696548</ref>. | |||
</StructureSection> | </StructureSection> | ||
