Nonstructural protein: Difference between revisions
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[[Nonstructural protein]] (NS) is a protein encoded by a virus which is not part of the viral particle<ref>PMID:23405236</ref>. Pestivirus encode a NS at the N-terminal of their polyproteins (Npro). For homology model and multiple sequence alignment see<br /> | <StructureSection load='1nhu' size='350' side='right' caption='Hepatitis virus nonstructural protein (PDB entry [[1nhu]])' scene=''> | ||
[[Nonstructural protein]] (NS) is a protein encoded by a virus which is not part of the viral particle<ref>PMID:23405236</ref>. Pestivirus encode a NS at the N-terminal of their polyproteins (Npro). For homology model and multiple sequence alignment see<br /> | |||
*[[User:Michael Strong/H1N1/NS]]<br /> | *[[User:Michael Strong/H1N1/NS]]<br /> | ||
*[[User:Michael Strong/H1N1/NS1/MSA]]<br /> | *[[User:Michael Strong/H1N1/NS1/MSA]]<br /> | ||
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*[[Student Project 4 for UMass Chemistry 423 Spring 2015]]. | *[[Student Project 4 for UMass Chemistry 423 Spring 2015]]. | ||
== Structural highlights == | |||
</StructureSection> | |||
== 3D Structures of Nonstructural protein == | == 3D Structures of Nonstructural protein == | ||
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**[[2hye]] – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5<br /> | **[[2hye]] – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5<br /> | ||
**[[2b5l]] - SvNSV + DNA damage-binding protein<br /> | **[[2b5l]] - SvNSV + DNA damage-binding protein<br /> | ||
**[[1nhv]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor<br /> | **[[1nhv]], [[1nhu]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor<br /> | ||
**[[1dxp]], [[1dy8]], [[1dy9]], [[1w3c]] – HvNS4A + HvHelicase NS3<br /> | **[[1dxp]], [[1dy8]], [[1dy9]], [[1w3c]] – HvNS4A + HvHelicase NS3<br /> | ||
**[[4k8b]] - HvNS4A + HvProtease NS3 + inhibitor<br /> | **[[4k8b]] - HvNS4A + HvProtease NS3 + inhibitor<br /> | ||