Plexin

spinqualitylabelsall models Glycosylated human plexin C1 (green) complex with semaphoric SEMA7A (grey) and Ca+2 ion (green) (PDB entry 3nvn) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Plexin (PLX) is the receptor for semaphorin. Plexin A controls axon guidance. Plexin B regulates Rho GTPase.

3D structures of plexin

05-July-2016

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• Plexin A
  • 3al8, 3oky – mPLX-A2 + semaphorin-6A – mouse
    
  • 4gza - mPLX-A2 + semaphorin-3A + neuropilin-1
    
  • 3al9, 3okt – mPLX-A2 extracellular domain
    
  • 3ig3 - mPLX-A3 intracellular domain
    
  • 3ryt - mPLX-A1 intracellular domain + Ras-related C3 botulinum toxin substrate
    
  • 3q3j - hPLX-A2 binding domain + Rho-related GTP-binding protein Rho6 – human
    
  • 4e74 - hPLX-A4 Rho GTPase-binding domain
• Plexin B
  • 2r2o – hPLX-B1 effector domain
  • 2rex - hPLX-B1 effector domain + Rho-related GTP-binding protein Rho6
  • 2jph - hPLX-B1 Rho GTPase-binding domain – NMR
    
  • 4e71 - hPLX-B2 Rho GTPase-binding domain
    
  • 3ol2 - hPLX-B1 + semaphorin 4D
  • 3sua, 3su8 – hPLX-B1 + RAS-related C3 botulinum toxin substrate
  • 3hm6 - hPLX-B1 cytoplasmic domain + peptide
• Plexin C
  • 3kuz - hPLX-C1 ubiquitin-like domain
  • 3nvn, 3nvq – hPLX-C1 + semaphorin 7A
• Plexin D
  • 3h6n - hPLX-D1 ubiquitin-like domain

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman