4a46: Difference between revisions
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== | ==Crosstalk between Cu(I) and Zn(II) homeostasis== | ||
[[4a46]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A46 OCA]. | <StructureSection load='4a46' size='340' side='right' caption='[[4a46]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4a46]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A46 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sb6|1sb6]], [[2xmt|2xmt]], [[2xmv|2xmv]], [[2xmm|2xmm]], [[2xmk|2xmk]], [[2xmj|2xmj]], [[2xmu|2xmu]], [[4a47|4a47]], [[4a48|4a48]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a46 OCA], [http://pdbe.org/4a46 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a46 RCSB], [http://www.ebi.ac.uk/pdbsum/4a46 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a46 ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins. | |||
Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.,Badarau A, Basle A, Firbank SJ, Dennison C Chem Commun (Camb). 2013 Sep 21;49(73):8000-2. doi: 10.1039/c3cc42709a. Epub 2013, Aug 7. PMID:23926594<ref>PMID:23926594</ref> | |||
<ref | |||
[[Category: Badarau, A | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
[[Category: Basle, A | </div> | ||
[[Category: Denninson, C | <div class="pdbe-citations 4a46" style="background-color:#fffaf0;"></div> | ||
[[Category: Firbank, S J | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Badarau, A]] | |||
[[Category: Basle, A]] | |||
[[Category: Denninson, C]] | |||
[[Category: Firbank, S J]] | |||
[[Category: Copper homeostasis]] | [[Category: Copper homeostasis]] | ||
[[Category: Metal-transporting atpase]] | [[Category: Metal-transporting atpase]] | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||
[[Category: Zinc homeostasis]] | [[Category: Zinc homeostasis]] | ||
