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==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==
==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==
<StructureSection load='3jtr' size='340' side='right' caption='[[3jtr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3jtr' size='340' side='right' caption='[[3jtr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._gk-16 Pseudomonas sp. gk-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2adv|2adv]], [[2ae4|2ae4]], [[2ae3|2ae3]], [[3jtq|3jtq]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2adv|2adv]], [[2ae4|2ae4]], [[2ae3|2ae3]], [[3jtq|3jtq]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [http://www.ebi.ac.uk/pdbsum/3jtr PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [http://pdbe.org/3jtr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [http://www.ebi.ac.uk/pdbsum/3jtr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtr ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jtr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3jtr" style="background-color:#fffaf0;"></div>
==See Also==
*[[Cephalosporin acylase|Cephalosporin acylase]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
[[Category: Pseudomonas sp]]
[[Category: Pseudomonas sp. gk-16]]
[[Category: Cho, K J]]
[[Category: Cho, K J]]
[[Category: Kim, J K]]
[[Category: Kim, J K]]

Revision as of 00:23, 5 August 2016

Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis

3jtr, resolution 2.50Å

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