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==Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin== | ==Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin== | ||
<StructureSection load='4raw' size='340' side='right' caption='[[4raw]], [[Resolution|resolution]] 1.30Å' scene=''> | <StructureSection load='4raw' size='340' side='right' caption='[[4raw]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkj|3rkj]], [[3rkk|3rkk]], [[3sbl|3sbl]], [[3sfp|3sfp]], [[3srx|3srx]], [[4gyq|4gyq]], [[4h0d|4h0d]], [[4hky|4hky]], [[4hl1|4hl1]], [[4gyu|4gyu]], [[4hl2|4hl2]], [[4ram|4ram]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkj|3rkj]], [[3rkk|3rkk]], [[3sbl|3sbl]], [[3sfp|3sfp]], [[3srx|3srx]], [[4gyq|4gyq]], [[4h0d|4h0d]], [[4hky|4hky]], [[4hl1|4hl1]], [[4gyu|4gyu]], [[4hl2|4hl2]], [[4ram|4ram]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4raw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4raw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4raw RCSB], [http://www.ebi.ac.uk/pdbsum/4raw PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4raw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4raw OCA], [http://pdbe.org/4raw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4raw RCSB], [http://www.ebi.ac.uk/pdbsum/4raw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4raw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | [[http://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
==See Also== | |||
*[[Beta-lactamase|Beta-lactamase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 05:25, 5 August 2016
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Beta-lactamase
- Babnigg, G
- Jedrzejczak, R
- Joachimiak, A
- Kim, Y
- Structural genomic
- MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors
- Sacchettini, J
- Tesar, C
- Alpha-beta-beta-alpha sandwich
- Hydrolase
- Hydrolase-antibiotic complex
- Mcsg
- Mtbi
- Psi-biology
- Structures of mtb proteins conferring susceptibility to known mtb inhibitor
