Apoptosis-inducing factor: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='4bur' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Apoptosis-inducing factor''' (AIF) is an intermembrane flavoprotein... |
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<StructureSection load='4bur' size='340' side='right' caption='Human apoptosis-inducing factor complex with FAD, NAD and sulfate 9PDB code [[4bur]])' scene=''> | |||
<StructureSection load='4bur' size='340' side='right' caption=' | |||
== Function == | == Function == | ||
'''Apoptosis-inducing factor''' (AIF) is an intermembrane flavoprotein which induces caspase-independent peripheral chromatin condensation and large-scale DNA fragmentation and thus causes cell death<ref>PMID:12022952</ref>. AIF contains the cofactor FAD. | '''Apoptosis-inducing factor''' (AIF) is an intermembrane flavoprotein which induces caspase-independent peripheral chromatin condensation and large-scale DNA fragmentation and thus causes cell death<ref>PMID:12022952</ref>. AIF contains the cofactor FAD. | ||
== Relevance == | == Relevance == | ||
