5llu: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~5llu is ON HOLD until Paper Publication~~

==Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5llu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LLU OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LLU FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5llm|5llm]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5llu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5llu OCA], [http://pdbe.org/5llu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5llu RCSB], [http://www.ebi.ac.uk/pdbsum/5llu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5llu ProSAT]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/EAA1_HUMAN EAA1_HUMAN]] Alternating hemiplegia of childhood;Episodic ataxia type 6. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/EAA1_HUMAN EAA1_HUMAN]] Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

__TOC__

</StructureSection>

[[Category: Assal, R]]

[[Category: Canul-Tec, J]]

[[Category: Legrand, P]]

[[Category: Reyes, N]]

[[Category: Excitatory amino acid transporter 1]]

[[Category: Human glutamate transporter]]

[[Category: Slc1a3]]

[[Category: Thermostabilized]]

[[Category: Transport protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5llu is ON HOLD  until Paper Publication
+==Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP==
+<StructureSection load='5llu' size='340' side='right' caption='[[5llu]], [[Resolution|resolution]] 3.32&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5llu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LLU FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5llm|5llm]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5llu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5llu OCA], [http://pdbe.org/5llu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5llu RCSB], [http://www.ebi.ac.uk/pdbsum/5llu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5llu ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/EAA1_HUMAN EAA1_HUMAN]] Alternating hemiplegia of childhood;Episodic ataxia type 6. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/EAA1_HUMAN EAA1_HUMAN]] Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
+__TOC__
+</StructureSection>
+[[Category: Assal, R]]
+[[Category: Canul-Tec, J]]
+[[Category: Legrand, P]]
+[[Category: Reyes, N]]
+[[Category: Excitatory amino acid transporter 1]]
+[[Category: Human glutamate transporter]]
+[[Category: Slc1a3]]
+[[Category: Thermostabilized]]
+[[Category: Transport protein]]