Response regulator: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 2: | Line 2: | ||
'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | '''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | ||
Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain. | Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain (DBD). | ||
*'''RR CheY''' is a chemotaxis response regulator in bacteria<ref>PMID:14563873</ref>. <br /> | *'''RR CheY''' is a chemotaxis response regulator in bacteria<ref>PMID:14563873</ref>. <br /> | ||
| Line 42: | Line 42: | ||
**[[2qsj]] – LuxR – ''Silicibbacter pomeroyi''<br/ > | **[[2qsj]] – LuxR – ''Silicibbacter pomeroyi''<br/ > | ||
**[[3cnb]], [[3eqz]] – MerR receiver domain – ''Colwellia psychrerythraea''<br/ > | **[[3cnb]], [[3eqz]] – MerR receiver domain – ''Colwellia psychrerythraea''<br/ > | ||
**[[2rnj]] – SaVraR | **[[2rnj]] – SaVraR DBD – ''Staphylococcus aureus'' – NMR<br/ > | ||
**[[2zxj]] - SaWalR | **[[2zxj]] - SaWalR DBD<br/ > | ||
**[[4gvp]] – SaVraR<br /> | **[[4gvp]] – SaVraR<br /> | ||
**[[4if4]] – SaVraR + Mg + BeF3<br /> | **[[4if4]] – SaVraR + Mg + BeF3<br /> | ||
**[[3q9s]] – DrRR receiver domain – ''Deinococcus radiodurans''<br/ > | **[[3q9s]] – DrRR receiver domain – ''Deinococcus radiodurans''<br/ > | ||
**[[3q9v]] - DrRR C terminal<br /> | **[[3q9v]] - DrRR C terminal<br /> | ||
**[[3rjp]] - RR | **[[3rjp]] - RR DBD – ''Streptococcus pyogenes''<br /> | ||
**[[2a9r]] – SpRR N terminal + phosphate + Mg | **[[2a9r]] – SpRR N terminal + phosphate + Mg | ||
| Line 62: | Line 62: | ||
**[[1mvo]] – BsPhoP receiver domain<br/ > | **[[1mvo]] – BsPhoP receiver domain<br/ > | ||
**[[2jb9]], [[2jba]] – EcPhoB (mutant) <br/ > | **[[2jb9]], [[2jba]] – EcPhoB (mutant) <br/ > | ||
**[[2pmu]] – MtPhoP | **[[2pmu]] – MtPhoP DBD | ||
*Polar differentiation response regulator | *Polar differentiation response regulator | ||
| Line 71: | Line 71: | ||
*Photosynthetic apparatus response regulator | *Photosynthetic apparatus response regulator | ||
**[[1umq]] – PrrA | **[[1umq]] – PrrA DBD – ''Rhodobacter sphaeroides'' – NMR<br/ > | ||
**[[1ys6]] – MtPrrA <br/ > | **[[1ys6]] – MtPrrA <br/ > | ||
**[[1ys7]] – MtPrrA + Mg | **[[1ys7]] – MtPrrA + Mg | ||
| Line 79: | Line 79: | ||
**[[1xhe]] – EcArcA receiver domain <br/ > | **[[1xhe]] – EcArcA receiver domain <br/ > | ||
**[[1xhf]] – EcArcA receiver domain + BeF3<BR/ > | **[[1xhf]] – EcArcA receiver domain + BeF3<BR/ > | ||
**[[4ynr]] - MtDevs GAF domain + CO<br /> | |||
**[[4yof]] - MtDevs GAF domain + NO<br /> | |||
**[[2y79]] – MtDevs GAF domain (mutant)<br /> | **[[2y79]] – MtDevs GAF domain (mutant)<br /> | ||
**[[3zxo]] - MtDevs ATP-binding domain (mutant)<br /> | **[[3zxo]] - MtDevs ATP-binding domain (mutant)<br /> | ||
| Line 102: | Line 104: | ||
**[[2zwm]] – BsYycF receiver domain<br/ > | **[[2zwm]] – BsYycF receiver domain<br/ > | ||
**[[3ulq]] – BsComA | **[[5iuj]], [[5iuk]], [[5iul]], [[5iun]] - BsDesR + DesK<br /> | ||
**[[3ulq]] – BsComA DBD + RR aspartate phosphatase<br /> | |||
**[[2pkx]] – EcPhoP regulatory domain<br /> | **[[2pkx]] – EcPhoP regulatory domain<br /> | ||
**[[5ed4]] - MtPhoP + DNA<br /> | |||
**[[3nhz]] – MtMtra N terminal<br /> | **[[3nhz]] – MtMtra N terminal<br /> | ||
**[[5fmn]] - SyInrS<br /> | |||
**[[5lwk]] - LpMaeR + BeF3 - ''Lactobacillus paracasei''<br /> | |||
**[[5lwl]] - LpMaeR (mutant)<br /> | |||
**[[4g9y]] - ScPcaV - ''Streptomyces coelicolor''<br /> | |||
**[[4fht]] - ScPcaV + hydroxybenzoic acid<br /> | |||
**[[4u88]] - SaSaeR DBD<br /> | |||
**[[4ixa]] - SaeR DBD - ''Staphylococcus epidermidis''<br /> | |||
**[[4so5]] - BasR + DNA - ''Klebsiella pneumoniae''<br /> | |||
*Stress response regulator | *Stress response regulator | ||
**[[3n0r]] – CVPhyR | **[[3n0r]] – CVPhyR<br /> | ||
**[[5i4c]] - EcRcsB receiver domain<br /> | |||
**[[3cra]], [[3crc]] - EcMazG<br /> | |||
**[[2v42]], [[2v43]] - EcRseB<br /> | |||
*Chemotaxis response regulator | *Chemotaxis response regulator see [[Chemotaxix protein]] | ||
*Two-component response regulator | *Two-component response regulator | ||
| Line 134: | Line 134: | ||
**[[2qr3]] – RR N terminal – ''Bacteroides fragilis''<br /> | **[[2qr3]] – RR N terminal – ''Bacteroides fragilis''<br /> | ||
**[[2qzj]] – RR – ''Clostridium difficile''<br /> | **[[2qzj]] – RR – ''Clostridium difficile''<br /> | ||
**[[3cz5]] – RR – ''Aurantimonas'' | **[[3cz5]] – RR – ''Aurantimonas''<br /> | ||
**[[2qvg]] - RR - ''Legionella pneumophila''<br /> | |||
**[[3ilh]] - RR - ''Cytophaga hutchinsonii''<br /> | |||
**[[5brj]] - RR - ''Agrobacterium tumefaciens''<br /> | |||
**[[5uic]] - QseB - ''Francisella tularensis''<br /> | |||
**[[3lsg]] - RR C-terminal - ''Fusobacterium nucleatum''<br /> | |||
**[[3p01]] - RR - Nostoc<br /> | |||
*response regulator receiver domain protein | *response regulator receiver domain protein | ||
Revision as of 20:19, 25 September 2017
| ||||||||||||
3D Structures of response regulator
Updated on 25-September-2017
References
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
