Disintegrin

spinqualitylabelsall models Disintegrin, 1z1x Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Disintegrins are a family of cysteine-rich toxins from viper venoms which inhibit platelet aggregation and cell adhesion. Over 100 disintegrins have been studied. Relevance Disintegrins, which have anti-integrin activity, have been the molecular scaffold used in the design of therapeutics for the prevention of thrombosis and cancer. Disintegrin also functions in inhibition of adipogenesis.

3D Structures of Disintegrin

Updated on 30-April-2018

2w9o, 2w9u, 2w9v, 2w9w – jerdostatin residues 68-110 – Trimeresurus jerdonii – NMR
1j2l – trimestatin - Trimeresurus flavovidrius
2pjf, 1q7i, 1q7j, 1n4y – Cr rhodostoxin residues 1-68 – Calloselasma rhodostoma – NMR
2pjg, 2pji, 2ljv - Cr rhodostoxin (mutant) – NMR
3uci - Cr rhodostoxin (mutant)
4rqg – Cr rhodostomin
4r5r, 4r5u – Cr rhodostomin (mutant)
1z1x, 1tej – Ec disintegrin – Echis carinatus
1rmr – Ec schistatin
1ro3, 2ech – Ec echistatin - NMR
1l3x – salmosin – Gloydius brevicaudus – NMR
1mpz – obtustatin – Macrovipera obtusa - NMR
3c05 – acostatin-α residues 48-109+acostatin-β residues 419-482 – copperhead
3dsl – bothropasin - Jararaca
2dw0, 2dw1, 2dw2 – catrocollastatin – rattlesnake
2mop, 2mp5 – bitistatin – African puff adder - NMR

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