Luciferase

spinqualitylabelsall models Luciferase (PDB code 3iep) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Luciferase (Luc) or luciferin monooxygenase (Lucmo)is an oxidative enzyme used in bioluminescence. It catalyzes the oxidation of the pigment luciferin producing oxyluciferin and light. See detailed analysis in Luciola cruciata luciferase Luciferase FMN complex- Vibrio harveyi Dinoflagellate luciferase Luciferase (Hebrew). See Colored & Bioluminescent Protein. Relevance Luc is used in biological research to assess gene transfection into cells where the Luc gene is added to the transfected gene and the light emission by Luc measured for indication of the transfection success.

3D Structures of Luciferase

Updated on 31-July-2018

{"openlevels":0}

• Luciferase
  • Luciola cruciata luciferase – fLuc+bromoform - firefly
    
  • Luciferase FMN complex- Vibrio harveyi – LtLuc (mutant) – Lampyris turkestanicus
    
  • Dinoflagellate luciferase – LtLuc
    
  • Luciferase (Hebrew) – VhLuc α+β chain+FMN – Vibrio harveyi
    
  • Colored & Bioluminescent Protein, 1brl - VhLuc α+β chain
    
  • 1bsl, 1xkj - VhLuc β chain
    
• Luciferin 2-monooxygenase
  • 2psd, 2psh, 2psj, 2pse, 2psf – Luc (mutant) – Renilla reniformis
    
  • 5b0u – Luc (mutant) catalytic subunit – luminous shrimp
    
• Luciferin 4-monooxygenase
  • 3iep, 1lci, 5dv9, 3ier – fLuc
    
  • 5kyt, 5kyv – fLuc (mutant)
    
  • 5dwv – fLuc+ substrate analog
    
  • 3ies, 3rix, 4e5d – fLuc+inhibitor
    
  • 4g36 – fLUc + dehydroluciferyl-sulfamoyl adenosine
    
  • 4g37 – fLUc (mutant) + dehydroluciferyl-sulfamoyl adenosine
    
  • 5gz2 – fLuc + thiazole derivative
    
  • 5gyz – fLuc + AMP + thiazole derivative
    
  • 5wys – fLuc + inhibitor
    
  • 2d1q – LcLuc (mutant)+MgATP – Luciola cruciata
    
  • 2d1r - LcLuc (mutant)+oxyluciferin+AMP
    
  • 2d1s, 2d1t - LcLuc (mutant)+intermediate analog
    
  • 2psd, 2psh, 2psj, 2pse, 2psf – Luc (mutant) – Renilla reniformis
    

Additional information

Luciferase (2d1s)

Several organisms are bioluminescent, meaning that they produce light. Luciferase is one of the enzymes that catalyzes light emitting reactions in organisms.

• For additional information, see: Colored & Bioluminescent Proteins

External Resources

• Yahoo news coverage of luciferase studies funded research for military applications
• Luciferase at Wikipedia
• Luciferase: June 2006 Molecule of the Month as part of the series of tutorials that are at the RCSB Protein Data Bank and written by David S. Goodsell

Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Alexander Berchansky, David Canner, Loïc Gazquez, Charlene Planchenault, Michal Harel